2017年12月6日星期三

CCG-203971|CCG-203971|cas 1443437-74-8

CCG-203971|CCG-203971|cas 1443437-74-8

DC Chemicals, Website: www.dcchemicals.com

Product Name: CCG-203971|Cas Number: 1443437-74-8| Catalog Number: DC10535|Other Nmaes: CCG 203971,CCG203971,CCG-203971

CCG-203971 is an inhibitor of SRE activation in the prostate cancer cell line PC-3 (IC50 = 6.4 μM), with 87% inhibition of SRE activation achieved at 100 μM.

CCG-203971 is an inhibitor of SRE activation in the prostate cancer cell line PC-3 (IC50 = 6.4 μM), with 87% inhibition of SRE activation achieved at 100 μM.2 This compound also inhibits PC-3 cell migration (IC50 = 4.2 μM), as determined by a scratch wound assay. CCG-203971 causes no cytotoxicity when evaluated by WST-1 assay.2 It is well tolerated in normal mice up to doses of 100 mg/kg given intraperitoneally over five days.

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