Lavendustin C (HDBA)|cas 125697-93-0
DC Chemicals, Website: www.dcchemicals.com
Product Name: Lavendustin C (HDBA)|Cas Number: 125697-93-0| Catalog Number: DC10596|Other Nmaes: NSC 666251
HDBA, a derivative of a Streptomyces griseolavendus butyl acetate extract, is a potent inhibitor of epidermal growth factor (EGF) receptor-associated tyrosine kinase with an IC50 value of 0.012 µM.
HDBA is a derivative of a Streptomyces griseolavendus butyl acetate extract, is a potent inhibitor of epidermal growth factor (EGF) receptor-associated tyrosine kinase with an IC50 value of 0.012 µM.HDBA also inhibits pp60c-src(+) kinase and Ca2+ calmodulin-dependent kinase II with IC50 values of 0.5 and 0.2 µM, respectively.At a concentration of 10-150 µM, HDBA inhibits tyrosine kinase-associated neutrophil degranulation and superoxide generation.
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