2017年12月6日星期三

BQCA|cas 338747-41-4

BQCA|cas 338747-41-4

DC Chemicals, Website: www.dcchemicals.com

Product Name: BQCA|Cas Number: 338747-41-4 | Catalog Number: DC10515

BQCA is a potent muscarinic M1 receptor positive allosteric modulator with selectivity for M1 over M2-M5.

BQCA is a potent muscarinic M1 receptor positive allosteric modulator with selectivity for M1 over M2-M5. Stimulation of the cortical muscarinic M1 receptor (CHRM1) is proposed as a treatment for schizophrenia, a hypothesis testable using CHRM1 allosteric modulators. BQCA binds allosterically to M1 to enhance the binding and efficacy of ACh at the receptor. M1 activation is a proposed mechanism for increasing information processing in disease states, such as Alzheimer′s.


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