2017年12月6日星期三

BT-11|BT11|LANCL2 modulator

BT-11|BT11|LANCL2 modulator

DC Chemicals, Website: www.dcchemicals.com

Product Name: BT-11|Cas Number: 1912399-75-7| Catalog Number: DC10460|Other Nmaes: BT11,BT 11

BT-11 is an orally active and selective LANCL2 modulator.

BT-11 is an orally active and selective LANCL2 modulator. BT-11 has demonstrated therapeutic efficacy in 3 validated mouse models of colitis at doses as low as 8 mg/kg/d. BT-11 at high doses has an excellent safety profile up to 1000 mg/kg/day. BT-11 protects from IBD by targeting LANCL2. BT-11 has potential to be a safe and effective orally active therapeutic for IBD. Lanthionine synthetase C-like 2 (LANCL2), a novel therapeutic target for inflammatory and autoimmune diseases and diabetes, exerts anti-inflammatory and insulin-sensitizing effects.


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