Autophinib|cas 1644443-47-9|VPS34 inhibitor
DC Chemicals, Website: www.dcchemicals.com
Product Name: Autophinib|Cas Number: 1644443-47-9| Catalog Number: DC10461
Autophinib is a novel potent autophagy inhibitor, inhibiting autophagy induced by starvation or Rapamycin by targeting the lipid kinase VPS34.
BT-11 is an orally active and selective LANCL2 modulator. BT-11 has demonstrated therapeutic efficacy in 3 validated mouse models of colitis at doses as low as 8 mg/kg/d. BT-11 at high doses has an excellent safety profile up to 1000 mg/kg/day. BT-11 protects from IBD by targeting LANCL2. BT-11 has potential to be a safe and effective orally active therapeutic for IBD. Lanthionine synthetase C-like 2 (LANCL2), a novel therapeutic target for inflammatory and autoimmune diseases and diabetes, exerts anti-inflammatory and insulin-sensitizing effects.
没有评论:
发表评论