WHI-P131(Janex 1)

WHI-P131(Janex 1)|DC Chemicals
Janex 1 selectively inhibits the tyrosine kinase activity of JAK3 with an IC50 value of 78 µM without affecting the enzymatic activity of JAK1, JAK2, or other protein tyrosine kinases (IC50 ≥350 µM).

Catlog: DC8077| Product name: WHI-P131(Janex 1)| Cas: 202475-60-3| Other names: WHIP-131,Janex-1)，WHIP131,Janex1| Molecule Formula: C16H15N3O3| MW: 297.31. Purity: >98%

Price: 100mg: 350 USD; 250mg: 650 USD; 1000mg: 1300 USD

Janex 1 selectively inhibits the tyrosine kinase activity of JAK3 with an IC50 value of 78 µM without affecting the enzymatic activity of JAK1, JAK2, or other protein tyrosine kinases (IC50 ≥350 µM).Janex 1 induces apoptosis in JAK3-expressing human leukemia cell lines NALM-6 and LC1;19, but not in melanoma or squamous carcinoma cell lines.

For research and scientific purpose only, not for human use.