AI-10-49 | CBFβ-SMMHC inhibitor|DC Chemicals

AI-10-49 | CBFβ-SMMHC inhibitor|DC Chemicals
AI-10-49 selectively binds to CBFβ-SMMHC and disrupts its binding to RUNX1.

Catlog: DC8064| Product name: AI-10-49| Cas: 1256094-72-0| Other names: AI 1049,AI1049 | Molecule Formula: C30H22F6N6O5| MW: 660.52. Purity: >98%

Price: 100mg: 600 USD; 250mg: 1100 USD; 1000mg: 2100 USD

AI-10-49 selectively binds to CBFβ-SMMHC and disrupts its binding to RUNX1. AI-10-49 restores RUNX1 transcriptional activity, displays favorable pharmacokinetics, and delays leukemia progression in mice. Treatment of primary inv(16) AML patient blasts with AI-10-49 triggers selective cell death.

For research and scientific purpose only, not for human use.