2015年5月31日星期日

PD 153035(AG-1517)|EGFR inhibitor|DC Chemicasl

PD 153035(AG-1517)|EGFR inhibitor|DC Chemicasl
PD 153035(AG-1517) is an ultra-potent inhibitor of epidermal growth factor receptor tyrosine kinase (EGFRK), with an IC50 of 25 pM.

Catlog: DC8078| Product name: PD 153035(AG-1517)| Cas: 153436-54-5| Other names: PD153035,AG1517,PD-153035,AG-1517| Molecule Formula: C16H14BrN3O2| MW: 360.21. Purity: >98%

Price: 100mg: 350 USD; 250mg: 650 USD; 1000mg: 1300 USD

An ultra-potent inhibitor of epidermal growth factor receptor tyrosine kinase (EGFRK), with an IC50 of 25 pM. Inhibits other tyrosine kinases at micromolar or higher concentrations. It selectively blocks EGF-mediated cellular processes including mitogenesis, early gene expression and oncogenic transformation. Inhibits the growth of a number of cancer cell lines. An extremely useful tool for exploring EGF-mediated cellular signaling.

For research and scientific purpose only, not for human use.

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