2015年5月31日星期日

AZD-3988(AZD3988)|DGAT-1 inhibitor|DC Chemicals

AZD-3988(AZD3988)|DGAT-1 inhibitor|DC Chemicals
AZD-3988 is a potent and selective diacylglycerol acyltransferase (DGAT-1) inhibitor (IC50 = 0.6 nM).

Catlog: DC8060| Product name: AZD-3988| Cas: 892489-52-0| Other names: AZD-3988, AZD3988, AZD 3988| Molecule Formula: C23H22F2N4O4| MW: 456.44. Purity: >98%

Price: 100mg: 800 USD; 250mg: 1500 USD; 1000mg: 2800 USD

Potent and selective diacylglycerol acyltransferase (DGAT-1) inhibitor (IC50 = 0.6 nM). Exhibits selectivity for DGAT-1 over DGAT-2, Kv11.1 (hERG) and cytochrome P450 enzymes. Suppresses triacylglyceride (TAG) plasma excursion and adipose tissue TAG synthesis in rats. Reduces body weight of diet-induced obese rats. Cell permeable and orally bioavailable.

For research and scientific purpose only, not for human use.

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