2015年5月31日星期日

PF-429242(PF429242)|S1P inhibitor|DC Chemicals

PF-429242(PF429242)|S1P inhibitor|DC Chemicals
PF-429242 is a potent inhibitor of S1P(cellular proprotein convertase sterol regulatory element-binding protein (SREBP) site 1 protease)

Catlog: DC8059| Product name: PF 429242| Cas: 947303-87-9| Other names: PF-429242,PF429242| Molecule Formula: C25H35N3O2.2HCl| MW: 482.49. Purity: >98%

Price: 100mg: 800 USD; 250mg: 1500 USD; 1000mg: 2800 USD

PF-429242 is a potent inhibitor of S1P (cellular proprotein convertase sterol regulatory element-binding protein (SREBP) site 1 protease) that reduces expression levels of hepatic SREBP target genes and lower rates of cholesterol and fatty acid synthesis in mice. PF-429242 is a potent antiviral agent against prototypic arenavirus lymphocytic choriomeningitis virus (LCMV) and LASV in cultured cells. PF-429242 efficiently prevented the processing of GPC from the LCMV and LASV. PF-429242 is expected to be active against CCHFV.

For research and scientific purpose only, not for human use.

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