DC Chemicals focus to develop Stem Cell related compounds.
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Stem cell
Compounds
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Cas No.
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Promoting
Pricing
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1
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CHIR99021
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252917-06-9
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price:
1600 USD/gram, 8000 USD/10grams. In stock.
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Highly
selective GSK-3 inhibitor; enables reprogramming of mouse embryonic
fibroblasts into iPS cells
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purity>98%
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2
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Y-27632 2HCL
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129830-38-2
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Price: 1700 USD/gram,
9000 USD/10grams, more than 30 grams in stock.
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Selective
p160ROCK inhibitor; increases survival rate of human embryonic stem cells
undergoing cryopreservation
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purity>99.5%
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3
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Thiazovivin
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1226056-71-8
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1300 USD/gram,
7500 USD/10grams. More than 35 grams In stock.
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Improves the
efficiency of fibroblast reprogramming and induction of iPSCs
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purity>98%
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4
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PD-0325901
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391210-10-9
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price:
1200 USD/gram, 6000 USD/10grams. More than 40 grams In stock.
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Selective
inhibitor of MEK1/2; enhances generation of iPSCs
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purity>99%,
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5
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A83-01
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price: 1800
USD/gram, 9500 USD/10grams. In stock.
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Selective
inhibitor of TGF-βRI, ALK4 and ALK7; maintains self-renewal of human iPSCs
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purity>98%
(By HNMR)
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6
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SB-431542
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301836-41-9
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price: 1200
USD/gram, 6000 USD/10grams. 15 grams In stock.
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Potent,
selective inhibitor of TGF-βRI, ALK4 and ALK7
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purity>99%,
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7
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CASIN
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425399-05-9
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1300 USD/gram,
7500 USD/10grams. In stock
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Cdc42 GTPase
inhibitor; functionally rejuvenates aged HSCs
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purity>98%
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8
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Dorsomorphin 2HCl
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Price: 1700
USD/gram, 9000 USD/10grams, more than 20 grams in stock.
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a potent inhibitor of AMP-activated protein
kinase (AMPK) (Ki=109nM) and bone morphogenic protein (BMP) signaling
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purity>98%
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9
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LDN-193189
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1062368-24-4
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price: 1800
USD/gram, 9500 USD/10grams. In stock.
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BMP pathway
inhibitor Inhibits ALK2, ALK3, ALK6
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purity>98%
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10
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StemRegenin 1
(SR1)
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1227633-49-9
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1200 USD/gram
4500 USD/5grams，7000 USD/10 grams, In stock
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Aryl
hydrocarbon receptor (AhR) antagonist
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purity>98%
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11
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A77-01
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An inhibitor
of ALK5 with an IC50 of 25nM
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12
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CHIR98014
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252935-94-7
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price: 1800
USD/gram, 9500 USD/10grams. 6 grams In stock.
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A selective
and ATP-competitive inhibitor of GSK-3β,higher activity than CHIR99021
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purity>99%,
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13
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BIO
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667463-62-9
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price:
1800 USD/gram,9000 USD/10grams. 10 grams In stock.
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Potent,
selective GSK-3 inhibitor
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purity>98%
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|
14
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GDC-0449
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879085-55-9
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price: 1200
USD/gram, 6000 USD/10grams
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GDC 0449 is a
potent antagonist of SMO that acts in a biphasic manner
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Purity>98%
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15
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NVP-LDE225
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956697-53-3
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price: 1300
USD/gram,6500 USD/10grams. In stock.
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A novel and
specific, orally bioavailable Smo inhibitor with an IC50 of 11 nM.
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purity>99%,
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16
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Repsox (ALK5
INHIBITOR)
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446859-33-2
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price: 1200
USD/gram, 6500 USD/10grams. More than 20 grams In stock.
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Selective
TGF-βRI inhibitor; enhances reprogramming efficiency
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purity>98%
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17
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XAV-939
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284028-89-3
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price: 1200
USD/gram, 6500 USD/10grams. More than 20 grams In stock.
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Tankyrase
inhibitor; promotes cardiomyogenesis
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purity>99%
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18
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DAPT
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208255-80-5
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price: 1000
USD/gram, 5500 USD/10grams. More than 15 grams In stock.
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A
gamma-secretase and indirectly Notch, LDL receptor-related protein,
E-cadherin and ErbB-4 inhibitor.
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purity>98%
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19
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GDC-0941
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957054-30-7
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price: 1200
USD/gram, 6000 USD/10grams, In stock
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Anovel class I
selective PI3K inhibitor
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purity>98%
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20
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LY-294002
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154447-36-6,
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price: 1200
USD/gram, 6000 USD/10grams.More than 20 grams In stock.
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Selective PI 3-kinase
inhibitor; suppresses proliferation of mESCs
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purity>99%
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21
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KY02111
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1118807-13-8
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price: 1200
USD/gram, 6000 USD/10grams.In stock.
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Promotes
differentiation of human ESCs and iPSCs into cardiomyocytes when used after
day three in culture
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Purity>98%
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22
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IWR-1-endo
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1127442-82-3
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price: 1200
USD/gram, 6000 USD/10grams. In stock.
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Axin
stabilizer; promotes β-catenin phosphorylation
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Purity>99%
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23
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IWP-2
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686770-61-6
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1800 USD/gram,
9000 USD/10grams. In stock.
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Inhibitor of
Wnt processing and secretion; suppresses self-renewal in R1 ESCs
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purity>98%
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25
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GANT-61
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500579-04-4
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price: 1200
USD/gram, 6000 USD/10grams. In stock.
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GLI
antagonist; inhibits Hh signaling
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Purity>98%
|
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26
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SB-203580
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152121-47-6
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price: 1200
USD/gram, 6000 USD/10grams. In stock.
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Selective
inhibitor of p38 MAPK; stimulates neural stem cell proliferation
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Purity>99%
|
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27
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BIX 01294
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935693-62-2
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1300 USD/gram,
9500 USD/10grams, In stock
|
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G9a-like
protein and G9a HMTase inhibitor; potentiates induction of iPSCs
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purity:>98%
|
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|
28
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JW 55
|
664993-53-7
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1300 USD/gram,
8000 USD/10grams, In stock
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Inhibitor of
the PARP domain of tankyrase 1 and 2 (TNKS1/2)
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purity:>98%
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29
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PluriSIn 1 (NSC
14613)
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91396-88-2
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1200
USD/gram, 8000 USD/10grams, In stock
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Inhibitor of
SCD1; selectively eliminates undifferentiated hPSCs from culture
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purity:>98%
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30
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Purmorphamine
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483367-10-8
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1600 USD/gram,
9500 USD/10grams, In stock
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Smo receptor
agonist; induces differentiation of mesenchymal progenitor cells into
osteoblasts
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purity:>98%
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|
31
|
AR-A014418
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487021-52-3,
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1200 USD/gram,
7000 USD/10 grams, In stock
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Selective
glycogen synthase kinase 3 (GSK-3) inhibitor (IC50 = 104 nM).
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purity>98%
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32
|
A 769662
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844499-71-4
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1200 USD/gram,
6000 USD/10grams , In stock
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Potent AMPK
activator; inhibits MSC proliferation
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purity:>98%
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33
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GW788388
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452342-67-5
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1200
USD/gram, 8000 USD/10grams, In stock
|
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Potent
inhibitor of transforming growth factor-β type I receptor (ALK5) (IC50 values
are 18 and 93 nM for ALK5 binding and for TGF-β cellular assay respectively).
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purity>98%
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34
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Forskolin
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66575-29-9
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1500 USD/gram,
8000 USD/10grams, In stock
|
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Used to
reprogram mouse embryonic fibroblasts to induced pluripotent stem cells
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purity>98%
|
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35
|
P7C3
|
301353-96-8
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1200
USD/gram, 8000 USD/10grams, In stock
|
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Neuroprotective
compound; enhances neurogenesis in vivo
|
purity:>98%
|
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36
|
MK-2206 2HCl
|
1032350-13-2
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1200 USD/gram,
7000 USD/10 grams, In stock
|
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AnAkt
inhibitor
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purity:>98%
|
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37
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ID-8
|
147591-46-6
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1200 USD/gram,
7000 USD/10 grams, In stock
|
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Sustains self-renewal
and pluripotency of ESCs
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purity:>98%
|
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38
|
FH1(BRD-K4477)
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CAS 2719-05-3
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1200
USD/gram, 8000 USD/10grams, In stock
|
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Enhances
differentiation of induced pluripotent stem cells (iPSCs) to hepatocytes and
promotes the maturation of iPSC-derived hepatocytes.
|
purity:>98%
|
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39
|
Reversine
|
656820-32-5
|
1200 USD/gram,
7000 USD/10 grams, In stock
|
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The first
organic molecule that has been demonstrated to reverse the cellular
differentiation process.
|
purity:>98%
|
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|
40
|
RG-108
|
48208-26-0
|
1200 USD/gram,
7000 USD/10 grams, In stock
|
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Non-nucleoside
DNA methyltransferase inhibitor; enhances efficiency of iPSC generation
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purity:>98%
|
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41
|
Wnt-C59
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1243243-89-1
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1200 USD/gram,
7000 USD/10 grams, In stock
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Wnt signaling
inhibitor; induces differentiation of iPSCs to cardiomyocytes
|
purity:>98%
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