NVP DPP 728 dihydrochloride supplier|DC Chemicals
DC Chemicals provides NVP DPP 728 dihydrochloride, other names: NVPDDP 728, NVP DPP728, cas: 247556-62-5. In stock.
Contact: website: www.dcchemicals.com,
sales@dcchemicals.com,order@dcchemicals.com,info@dcchemicals.com,
Tel: +86-21-58447131;Fax:+86-21-61643318;
NVP DPP 728 is a potent and orally active inhibitor of dipeptidyl peptidase (DPP)-IV with Ki and IC50 values of 11 nM and 14 nM, respectively.
NVP DPP 728 dihydrochloride, other names: NVPDDP 728, NVP DPP728, cas: 247556-62-5, Molecule formular: , Molecule Weight: , Chemical name: 6-[[2-[[2-(2S)-2-Cyano-1-pyrrolidinyl]-2-oxoethyl]amino]ethyl]amino-3-pyridinecarbononitrile dihydrochloride
Potent, orally active dipeptidyl peptidase (DPP)-IV inhibitor (Ki = 11 nM, IC50 = 14 nM) that displays > 15 000-fold selectivity over DPP-II and a range of proline-cleaving proteases. Exhibits antidiabetic activity in vivo; improves glucose tolerance, increases glucagon-like peptide 1 (GLP-1) and insulin levels, augments insulin secretion and GLUT2 levels, and reduces (preserves) islet size. For the detailed information of NVP DPP 728 dihydrochloride, the solubility of NVP DPP 728 dihydrochloride in water, the solubility of NVP DPP 728 dihydrochloride in DMSO, the solubility of NVP DPP 728 dihydrochloride in PBS buffer, the animal experiment (test) of NVP DPP 728 dihydrochloride, the cell expriment (test) of NVP DPP 728 dihydrochloride, the in vivo, in vitro and clinical trial test of NVP DPP 728 dihydrochloride, the EC50, IC50,and affinity,of NVP DPP 728 dihydrochloride, Please contact DC Chemicals.
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