DC Chemicals Supply: PS48, Cas: 1180676-32-7 ,Cat No. DC7484, Purity>98%, In stock.
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PS48|cas 1180676-32-7, Synonym name: PS-48,PS 48, Chemical name: 5-(4-Chloro-phenyl)-3-phenyl-pent-2-enoic acid, Molecule weight: 286.75, Molecule Formula: C17H15ClO2
PS48 is a PDK1 (phosphoinositide-depende?nt protein kinase 1) activator which binds to the HM/PIF binding pocket rather than the ATP-binding site. PS48 is one of only a few truly allosteric compounds targeting a regulatory binding site on a protein kinase catalytic domain that is not adjacent to or overlapping with the ATP-binding site.
PS48 is a PDK1 (phosphoinositide-depende?nt protein kinase 1) activator which binds to the HM/PIF binding pocket rather than the ATP-binding site. PS48 is one of only a few truly allosteric compounds targeting a regulatory binding site on a protein kinase catalytic domain that is not adjacent to or overlapping with the ATP-binding site.
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