DC Chemicals Supply: Uramustine, Cas: 66-75-1 ,Cat No. DC7524, Purity>98%, In stock.
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Uramustine|cas 66-75-1, Synonym name: uracil mustard; Demethyldopan, Desmethyldopan, Uracilmostaza, Uracillost, Uramustin, Nordopan, Chlorethaminacil, Aminouracil mustard, Uramustina, Uramustinum, Uracil lost, Uracil nitrogen mustard, 5-Aminouracil mustard, Uramustine (INN), Uracil lost [German], Uracil mustard (TN), Uramustinum [INN-Latin], Uramustina [INN-Spanish], Chemical name: 5-[bis(2-chloroethyl)amino]-1H-pyrimidine-2,4-dione, Molecule weight: 252.09784, Molecule Formula: C8H11Cl2N3O2
Uramustine (INN), also known as uracil mustard, is a chemotherapy drug which belongs to the class of alkylating agents. It is used in lymphatic malignancies such as non-Hodgkin's lymphoma. It works by damaging DNA, primarily in cancer cells that preferentially take up the uracil due to their need to make nucleic acids during their rapid cycles of cell division. The DNA damage leads to apoptosis of the affected cells. Bone marrow suppression and nausea are the main side effects. Chemically it is a derivative of nitrogen mustard and uracil.
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