WZB117|WZB-117|glucose transporter 1 (Glut1) inhibitor.
DC Chemicals, Website: www.dcchemicals.com
Product Name: WZB117|Cas Number: 1223397-11-2| Catalog Number: DC10493|Other Nmaes: WZB117,WZB-117,WZB 117
WZB117 is an irreversible inhibitor of glucose transporter 1 (Glut1) that blocks glucose transport in diverse cancer cells (IC50 = ~0.6 µM), reducing extracellular lactate and intracellular ATP levels.
WZB117 is an irreversible inhibitor of glucose transporter 1 (Glut1) that blocks glucose transport in diverse cancer cells (IC50 = ~0.6 µM), reducing extracellular lactate and intracellular ATP levels. It inhibits cancer cell proliferation (IC50s = 5-10 µM), resulting in cell cycle arrest, senescence, and necrosis or apoptosis.
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