Tyrphostin AG-555|AG555|EGFR inhibitor

Tyrphostin AG-555|AG555|EGFR inhibitor

DC Chemicals, Website: www.dcchemicals.com

Product Name: Tyrphostin AG-555|Cas Number: 133550-34-2| Catalog Number: DC10468|Other Nmaes: Tyrphostin AG 555,Tyrphostin AG-555,Tyrphostin AG555

Tyrphostin AG 555 is a potent epidermal growth factor receptor kinase inhibitor.

AG 555 is a potent EGFR (epidermal growth factor receptor) kinase inhibitor (IC50 = 0.7 μM) that displays 50-fold and >140-fold selectivity over ErbB2 and insulin receptor kinase respectively. AG 555 induces G1 growth arrest selectively in transformed cells (IC50 values are 6.4 and 9.4 μM in HPV16-immortalized and normal keratinocytes respectively).