KIN1148|KIN-1148|cas 1428729-56-9|IRF3 agonist
DC Chemicals, Website: www.dcchemicals.com
Product Name: KIN1148|Cas Number: 1428729-56-9| Catalog Number: DC10518|Other Nmaes: KIN1148,KIN-1148,KIN 1148
KIN1148, a small-molecule IRF3 agonist, is a novel influenza vaccine adjuvant found to enhance flu vaccine efficacy.
KIN1148 induces the dose-dependent nuclear translocation of IRF3 in PH5CH8 cells and specific activation of IRF3- responsive promoters. KIN1148 also elicits greater induction of endogenous IRF3-dependent ISG54 and OASL expression by PH5CH8 cells.
没有评论:
发表评论