Delafloxacin (RX-3341, ABT-492)|cas 189279-58-1
DC Chemicals, Website: www.dcchemicals.com
Product Name: Delafloxacin(ABT-492)|Cas Number: 189279-58-1| Catalog Number: DC10458|Other Nmaes: Delafloxacinum; RX-3341; WQ-3034; ABT492; ABT 492; ABT-492,WQ3034,WQ 3034
Delafloxacin (RX-3341, ABT-492) is a fluoroquinolone antibiotic agent.
ABT-492 was more potent against quinolone-susceptible and -resistant gram-positive organisms, had activity similar to that of ciprofloxacin against certain members of the family Enterobacteriaceae, and had comparable activity against quinolone-susceptible, nonfermentative, gram-negative organisms.
in vitro: ABT-492 exhibited excellent in vitro activities against all 326 aerobic and anaerobic antral puncture sinus isolates tested with MICs (in micrograms per milliliter) at which 90% of the isolates tested were inhibited as follows: Haemophilus influenzae, 0.001; Moraxella catarrhalis, 0.008; and Streptococcus pneumoniae, 0.015. ABT-492 was as active as trovafloxacin against Chlamydia trachomatis, indicating good intracellular penetration and antibacterial activity.
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