Nicaraven supplier|DC Chemicals
DC Chemicals provides Nicaraven, other names: , cas: 79455-30-4. In stock.
Contact: website: www.dcchemicals.com,
sales@dcchemicals.com,order@dcchemicals.com,info@dcchemicals.com,
Tel: +86-21-58447131;Fax:+86-21-61643307；
Nicaraven is an antivasospastic substance.
Nicaraven, other names: , cas: 79455-30-4, Molecule formular: C15-H16-N4-O2, Molecule Weight: 284.32, Chemical name: N-[1-(pyridine-3-carbonylamino)propan-2-yl]pyridine-3-carboxamide
Nicaraven is a novel free radical scavenger. Nicaraven inhibits human platelet aggregation in vitro. The maximum aggregation rate induced by adenosine diphosphate (ADP) was significantly inhibited by nicaraven at concentration ranges of 3.50 x 10(-4) mol/L or higher in the healthy volunteer platelets. The maximum aggregation rate induced by collagen was significantly inhibited by 1.75 x 10(-3) mol/L of nicaraven. Using platelets from patients with cerebral thrombosis, the maximum aggregation rate induced by ADP was significantly inhibited by 1.75 x 10(-3) mol/L of nicaraven. Furthermore, the maximum aggregation rate induced by collagen were significantly reduced by 1.75 x 10(-3) mol/L of nicaraven. Nicaraven induces dose-dependent inhibition of platelet aggregation in both healthy volunteers and patients with cerebral thrombosis. For the detailed information of Nicaraven, the solubility of Nicaraven in water, the solubility of Nicaraven in DMSO, the solubility of Nicaraven in PBS buffer, the animal experiment (test) of Nicaraven, the cell expriment (test) of Nicaraven, the in vivo, in vitro and clinical trial test of Nicaraven, the EC50, IC50,and affinity,of Nicaraven, Please contact DC Chemicals.
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