GDC-0623 supplier| G-868|DC Chemicals

GDC-0623 supplier| G-868|DC Chemicals
DC Chemicals provides GDC-0623, other names:  G-868, cas: 1168091-68-6. In stock.

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GDC-0623 is a potent, ATP-uncompetitive inhibitors of MEK1(Ki=0.13 nM, +ATP).

GDC-0623, other names:  G-868, cas: 1168091-68-6, Molecule formular: C16H14FIN4O3, Molecule Weight: 456.21, Chemical name: 5-(2-Fluoro-4-iodophenylamino)imidazo[1,5-a]pyridine-6-carboxylic acid N-(2-hydroxyethoxy)amide; RG 7421

GDC-0623 is a potent, ATP-uncompetitive inhibitors of MEK1(Ki=0.13 nM, +ATP); 6-fold weaker potency against HCT116 (KRAS(G13D), EC50=42 nM) versus A375 (BRAF(V600E), EC50=7 nM). For the detailed information of GDC-0623, the solubility of GDC-0623 in water, the solubility of GDC-0623 in DMSO, the solubility of GDC-0623 in PBS buffer, the animal experiment (test) of  GDC-0623, the cell expriment (test) of GDC-0623, the in vivo, in vitro and clinical trial test of GDC-0623, the EC50, IC50,and affinity,of GDC-0623, Please contact DC Chemicals.