2015年4月1日星期三

AZD6482 supplier| AZD-6482|DC Chemicals

 AZD6482 supplier| AZD-6482|DC Chemicals
DC Chemicals provides  AZD6482, other names:  AZD-6482, AZD 6482, cas: 1173900-33-8. In stock.

Contact: website: www.dcchemicals.com,
sales@dcchemicals.com,order@dcchemicals.com,info@dcchemicals.com,
Tel: +86-21-58447131;Fax:+86-21-61643334;

AZD6482 is a PI3Kβ inhibitor with IC50 of 10 nM, 8-, 87- and 109-fold more selective to PI3Kβ than PI3Kδ, PI3Kα and PI3Kγ.

 AZD6482, other names:  AZD-6482, AZD 6482, cas: 1173900-33-8, Molecule formular: C22H24N4O4, Molecule Weight: 408.45, Chemical name: (-)-2-[[(1R)-1-[7-Methyl-2-(4-morpholinyl)-4-oxo-4H-pyrido[1,2-a]pyrimidin-9-yl]ethyl]amino]benzoic acid

AZD6482 is a PI3Kβ inhibitor with IC50 of 10 nM, 8-, 87- and 109-fold more selective to PI3Kβ than PI3Kδ, PI3Kα and PI3Kγ.AZD6482 is a PI3Kβ inhibitor (IC50=0.021μM) used in antithrombotic therapy. AZD6482 targets a process that is critical to pathological thrombus formation without interfering with normal haemostasis, which avoids the drawbacks of the existing anti-thrombotic therapy. AZD6482 inhibits PI3Kβ/α/γ/δwith IC50 of 0.021, 1.4, 1.2, 0.08μM, respectively. It washed platelet aggregation with concentration at 6 nM.
 For the detailed information of  AZD6482, the solubility of  AZD6482 in water, the solubility of  AZD6482 in DMSO, the solubility of  AZD6482 in PBS buffer, the animal experiment (test) of   AZD6482, the cell expriment (test) of  AZD6482, the in vivo, in vitro and clinical trial test of  AZD6482, the EC50, IC50,and affinity,of  AZD6482, Please contact DC Chemicals.

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