DC Chemicals supplies: TAPI-1,cas: 171235-71-5,Catalog: DC7560,In stock.
Contact: website: www.dcchemicals.com,
sales@dcchemicals.com,order@dcchemicals.com,info@dcchemicals.com,
Tel: +86-21-58447131;Fax:+86-21-61643258；
Product name: TAPI-1, Synonyms: N-(R)-[2-(Hydroxyaminocarbonyl)methyl]-4-methylpentanoyl-L-naphthylalanyl-L-alanine, 2-aminoethyl Amide, TNF-α Protease Inhibitor-1, cas: 171235-71-5, MW: 499.6, Molecule Formula: C??H??N?O?
TAPI-1, cas 171235-71-5, Purity>98%. Best price and quality from DC Chemicals.
A structural analog of TAPI-0 (Cat. No. 579050) with similar in vitro efficacy For the inhibition of MMPs and TACE (TNF-α converting enzyme/ADAM17). TAPI-1 also blocks the shedding of several cell surface proteins such as IL-6 receptor, p60 TNF receptor, and p80 TNF receptor. Blocks constitutive (IC50 = 8.09 ?M) and muscarinic receptor-stimulated (IC50 = 3.61 ?M) sAAPα release in HEK 293 cells expressing M3 muscarinic receptors. A 10 mM (500 ?g/100 ?l) solution of TAPI-1 (Cat. No. 579050) in DMSO is also available.For the detailed information of TAPI-1, the solubility of TAPI-1 in water, the solubility of TAPI-1 in DMSO, the solubility of TAPI-1 in PBS buffer, the animal experiment (test) of TAPI-1, the cell expriment (test) of TAPI-1, the in vivo, in vitro and clinical trial test of TAPI-1, the EC50, IC50,and Affinity of TAPI-1, Please contact DC Chemicals.
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