OTS-964(TOPK Inhibitor)|From DC Chemicals

OTS-964(TOPK Inhibitor)|From DC Chemicals
DC Chemicals provides OTS-964 HCL, other names: OTS964， OTS 964, cas: 1338545-07-5. In stock.

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OTS964 is a novel TOPK(T–lymphokine-activated killer cell–originated protein kinase)  inhibitor.

OTS-964 HCL, other names: OTS964， OTS 964, cas: 1338545-07-5, Molecule formular: C23H25ClN2O2S, Molecule Weight: 428.1, Chemical name: (R)-9-(4-(1-(dimethylamino)propan-2-yl)phenyl)-8-hydroxy-6-methylthieno[2,3-c]quinolin-4(5H)-one

OTS964 is a novel TOPK(T–lymphokine-activated killer cell–originated protein kinase)  inhibitor.Similar to the knockdown effect of TOPK small interfering RNAs (siRNAs), OTS964 causes a cytokinesis defect and the subsequent apoptosis of cancer cells in vitro as well as in xenograft models of human lung cancer.OTS964 delivered in a liposomal formulation effectively caused complete regression of transplanted tumors without showing any adverse reactions in mice.For the detailed information about the solubility of OTS-964  in water, the solubility of OTS-964  in DMSO, the solubility of OTS-964  in PBS buffer, the animal experiment of OTS-964 ,the in vivo and in vitro test of OTS-964 ,the cell experiment of OTS-964 ,the IC50 and EC50 of OTS-964  please contact DC Chemicals.