DC Chemicals supplies: MM-102,cas: 1417329-24-8,Catalog: DC7562,In stock.
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Product name: MM-102, Synonyms: HMTase Inhibitor IX, cas: 1417329-24-8, MW: 669.8, Molecule Formula: C35H49F2N7O4
MM-102, cas 1417329-24-8, Purity>98%. Best price and quality from DC Chemicals. Cilengitide is a potent integrin inhibitor for αvβ3 receptor and αvβ5 receptor with IC50 of 4.1 nM and 79 nM, respectively; ~10-fold selectivity against gpIIbIIIa. Phase 2.
MM-102, as a MLL1 mimetic, shows high binding affinities to WDR5 with IC50 of 2.9 nM and Ki of < 1 nM. In the MLL1-AF9 transduced murine cells, MM-102 specifically reduces expression of two critical MLL1 target genes (HoxA9 and Meis-1), which are required For MLL1 mediated leukemogenesis. In addition, MM-102 effectively and selectively inhibits cell growth and induces apoptosis in leukemia cells harboring MLL1 fusion proteins. [1]For the detailed information of MM-102, the solubility of MM-102 in water, the solubility of MM-102 in DMSO, the solubility of MM-102 in PBS buffer, the animal experiment (test) of MM-102, the cell expriment (test) of MM-102, the in vivo, in vitro and clinical trial test of MM-102, the EC50, IC50,and Affinity of MM-102, Please contact DC Chemicals.
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