2015年4月1日星期三

CLOZAPINE N-OXIDE supplier||DC Chemicals

CLOZAPINE N-OXIDE supplier||DC Chemicals
DC Chemicals provides CLOZAPINE N-OXIDE, other names: , cas: 34233-69-7. In stock.

Contact: website: www.dcchemicals.com,
sales@dcchemicals.com,order@dcchemicals.com,info@dcchemicals.com,
Tel: +86-21-58447131;Fax:+86-21-61643321;

Clozapine N-oxide is a major metabolite of Clozapine noted to decrease SR-2A (5-HT2 serotonin receptor) density in vitro.

CLOZAPINE N-OXIDE, other names: , cas: 34233-69-7, Molecule formular: C18H19ClN4O, Molecule Weight: 342.82, Chemical name: 8-​Chloro-​11-​(4-​methyl-​1-​piperazinyl)​-​5H-​dibenzo[b,e]​(1,4)​diazepine N-oxide

Clozapine N-oxide is a major metabolite of Clozapine (sc-200402) noted to decrease SR-2A (5-HT2 serotonin receptor) density in vitro. Clozapine N-oxide was noted to decrease 5-HT2 serotonin receptor density in rat primary cortical cells and human hippocampal SHS5Y5 neuroblastoma cells.Clozapine and N-desmethylclozapine antagonized 5-HT-stimulated phosphoinositide hydrolysis with IC50 values of 110 and 29.4 nM, respectively. Clozapine N-oxide was less potent  For the detailed information of CLOZAPINE N-OXIDE, the solubility of CLOZAPINE N-OXIDE in water, the solubility of CLOZAPINE N-OXIDE in DMSO, the solubility of CLOZAPINE N-OXIDE in PBS buffer, the animal experiment (test) of  CLOZAPINE N-OXIDE, the cell expriment (test) of CLOZAPINE N-OXIDE, the in vivo, in vitro and clinical trial test of CLOZAPINE N-OXIDE, the EC50, IC50,and affinity,of CLOZAPINE N-OXIDE, Please contact DC Chemicals.

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