CEP-37440 supplier||DC Chemicals

CEP-37440 supplier||DC Chemicals
DC Chemicals provides CEP-37440, other names: , cas: 1391712-60-9. In stock.

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CEP-37440 is a novel potent and selective Dual FAK/ALK inhibitor with IC50 s of 2.3 nM (FAK) and 120 nM(ALK cellular IC50 in 75% human plasma).

CEP-37440, other names: , cas: 1391712-60-9, Molecule formular: C30H38ClN7O3, Molecule Weight: 580.12, Chemical name: (S)-2-((5-chloro-2-((6-(4-(2-hydroxyethyl)piperazin-1-yl)-1-methoxy-6,7,8,9-tetrahydro-5H-benzo[7]annulen-2-yl)amino)pyrimidin-4-yl)amino)-N-methylbenzamide

CEP-37440 is a novel potent and selective Dual FAK/ALK inhibitor with IC50 s of 2.3 nM (FAK) and 120 nM(ALK cellular IC50 in 75% human plasma).Preparation of fused bicyclic 2,4-diaminopyrimidine derivatives as a dual ALK and FAK inhibitor
By Jacobs, Martin J.; Ott, Gregory R.
From PCT Int. Appl. (2013), WO 2013134353 A1 20130912. For the detailed information of CEP-37440, the solubility of CEP-37440 in water, the solubility of CEP-37440 in DMSO, the solubility of CEP-37440 in PBS buffer, the animal experiment (test) of  CEP-37440, the cell expriment (test) of CEP-37440, the in vivo, in vitro and clinical trial test of CEP-37440, the EC50, IC50,and affinity,of CEP-37440, Please contact DC Chemicals.