DC Chemicals supplies: AZD1981,cas: 802904-66-1,Catalog: DC7572,In stock.
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Product name: AZD1981, Synonyms: , cas: 802904-66-1, MW: 388.87, Molecule Formula: C19H17ClN2O3S
AZD1981, cas 802904-66-1, Purity>98%. Best price and quality from DC Chemicals. PD-173955 is a src tyrosine kinase inhibitor. PD173955 inhibited Bcr-Abl-dependent cell growth.
AZD1981, as a potent antagonist in a disease relevant cell system, inhibits DK-PGD2-induced CD11b expression in human eosinophils with IC50 of 10 nM. [1] AZD1981 blocks DP2-mediated shape change in human eosinophils and basophils in blood, as well as DP2-mediated chemotaxis of human Th2 cells and eosinophils. Moreover, AZD1981 also blocks the binding of [3H]PGD2 to mouse, rat, guinea pig, rabbit and dog recombinant DP2. [2] AZD1981 has high oral bioavailability in male sprague dawley rats. [1] In guinea pig hind limb model, AZD1981 (100 nM) completely inhibits DK-PGD2-induced eosinophil mobilization. [2]For the detailed information of AZD1981, the solubility of AZD1981 in water, the solubility of AZD1981 in DMSO, the solubility of AZD1981 in PBS buffer, the animal experiment (test) of AZD1981, the cell expriment (test) of AZD1981, the in vivo, in vitro and clinical trial test of AZD1981, the EC50, IC50,and Affinity of AZD1981, Please contact DC Chemicals.
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