Sorafenib (BAY-43-9006)From supplier |DC Chemicals

Sorafenib (BAY-43-9006)From supplier |DC Chemicals

Sorafenib(BAY 43-9006) is a potent inhibitor of Raf-1 with IC50 values of 6 nM, 22 nM and 90 nM for Raf-1, B-Raf, and VEGFR2 respectively, BAY 43-9006 suppresses both wild-type and V599E mutant BRAF activity in vitro.

Product Name: nmj8nmj8nmj8|Cat No.:DC8791|CAS: 284461-73-0|Other names: Bay 43-9006,Bay43-9006|MW: 464.83|C21H16ClF3N4O3

Sorafenib tosylate is the tosylate salt of sorafenib, a synthetic compound targeting growth signaling and angiogenesis. Sorafenib blocks the enzyme RAF kinase, a critical component of the RAF/MEK/ERK signaling pathway that controls cell division and proliferation; in addition, sorafenib inhibits the VEGFR-2/PDGFR-beta signaling cascade, thereby blocking tumor angiogenesis. Check  For active clinical trials or closed clinical trials using this agent. (NCI Thesaurus).

 For the detailed information about the solubility of Sorafenib (BAY-43-9006) in water, the solubility of Sorafenib (BAY-43-9006) in DMSO, the solubility of Sorafenib (BAY-43-9006) in PBS buffer, the animal experiment（test） of Sorafenib (BAY-43-9006),the in vivo,in vitro and clinical trial test of Sorafenib (BAY-43-9006),the cell experiment（test） of Sorafenib (BAY-43-9006),the IC50, EC50 and Affinity of Sorafenib (BAY-43-9006), please contact DC Chemicals.

For research only, not for human use!