2016年3月14日星期一

Dutasteride|CAS 164656-23-9|DC Chemicals

Dutasteride|CAS 164656-23-9|DC Chemicals

Dutasteride is a 5-α-reductase inhibitor that inhibits the conversion of testosterone into dihydrotestosterone (DHT). 

Product Name: Dutasteride|Cat No.:DC8825|CAS: 164656-23-9|Other names: GI 198745|MW: 528.53|C27H30F6N2O2

Dutasteride is a 5-α-reductase inhibitor that inhibits the conversion of testosterone into dihydrotestosterone (DHT). Dutasteride inhibits both isoforms of 5-α reductase (5 α-Reductase 1/5aR1 and 5 α-Reductase 2/5aR2) to a similar extent (IC50 6nmol/l and 7 nmol/l, respectively), while finasteride only inhibits Type II. Dutasteride competed for binding the LNCaP cell AR with an IC50 approximately 1.5 μM.

For research only, not for human use!

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