DB07268 is a potent and selective JNK1 inhibitor with an IC50 value of 9 nM.
DB07268 is a potent and selective JNK1 inhibitor with an IC50 value of 9 nM. This compound has some degree of selectivity over quite a few kinases with the exceptions of CHK1, CK2, and PLK. Although compound 2b(DB-07268) shows submicromolar potency against these three kinases, it still appears to exhibit at least 70- to 90-fold greater potency against JNK1 than CHK1, CK2, and PLK.
For research only, not for human use!
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