APD597(JNJ-38431055) is a GPR119 agonist intended for the treatment of type 2 diabetes, with EC50 of 46 nM for hGPR119.
Product Name: APD-597|Cat No.:DC8804|CAS: 897732-93-3|Other names: JNJ-38431055; APD-597; APD 597; JNJ38431055; JNJ 38431055|MW: 479.55|C21H29N5O6S
APD597 is a GPR119 agonist intended for the treatment of type 2 diabetes, with EC50 of 46 nM for hGPR119. The design and synthesis of a second generation GPR119-agonist clinical candidate for the treatment of diabetes is described. APD597 was selected for preclinical development based on a good balance between agonist potency, intrinsic activity and in particular on its good solubility and reduced drug-drug interaction potential.
For research only, not for human use!
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