PCI-32765 (Ibrutinib) |cas 936563-96-1 |DC Chemicals|Supplier|Price|Buy

DC Chemicals Supply: PCI-32765 (Ibrutinib) ,cas 936563-96-1, Cat No. DC1106, In stock

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Product name: PCI-32765 (Ibrutinib), Synonym:　PCI32765, Cat No. DC1106, Cas: 936563-96-1, Chemical Name:(R)-1-(3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)prop-2-en-1-one, Molecular Formula: C25H24N6O2, MW: 440.5

PCI-32765 (Ibrutinib) Cas#936563-96-1.Purity:>98%.Best Price and Quality in the Market!Supplied by DC Chemicals! PCI-32765 (Ibrutinib) is a potent and highly selective Btk inhibitor with IC50 of 0.5 nM.

Description of Ibrutinib (PCI-32765): Ibrutinib is a BTK inhibitor, is also an orally bioavailable small-molecule inhibitor of Bruton's tyrosine kinase (BTK) with potential antineoplastic activity. BTK inhibitor PCI-32765 binds to and inhibits BTK activity, preventing B-cell activation and B-cell-mediated signaling and inhibiting the growth of malignant B cells that overexpress BTK. BTK, a member of the src-related BTK/Tec family of cytoplasmic tyrosine kinases, is required for B cell receptor (BCR) signaling, plays a key role in B-cell maturation, and is overexpressed in a number of B-cell malignancies. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus).

For the detailed information about the solubility of PCI-32765 (Ibrutinib) in water, the solubility of PCI-32765 (Ibrutinib) in DMSO, the solubility of PCI-32765 (Ibrutinib) in PBS buffer, the animal experiment of PCI-32765 (Ibrutinib),the in vivo and in vitro test of PCI-32765 (Ibrutinib),the cell experiment of PCI-32765 (Ibrutinib),the IC50 and EC50 of PCI-32765 (Ibrutinib)please contact DC Chemicals.