Crizotinib (PF-2341066) |cas 877399-52-5 |DC Chemicals|Supplier|Price|Buy

DC Chemicals Supply: Crizotinib (PF-2341066) ,cas 877399-52-5, Cat No. DC2047, In stock

Contact: website: www.dcchemicals.com,

sales@dcchemicals.com,order@dcchemicals.com,info@dcchemicals.com,

Tel: +86-21-61454686;Fax:+86-21-61642563；

Product name: Crizotinib (PF-2341066), Synonym:　PF 2341066, PF2341066, Cat No. DC2047, Cas: 877399-52-5, Chemical Name:3-((R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy)-5-(1-(piperidin-4-yl)-1H-pyrazol-4-yl)pyridin-2-amine, Molecular Formula: C21H22Cl2FN5O, MW: 450.34

Crizotinib (PF-2341066) Cas#877399-52-5.Purity:>98%.Best Price and Quality in the Market!Supplied by DC Chemicals! PF-2341066 (Crizotinib) is a potent inhibitor of c-Met and ALK with IC50 of 11 nM and 24 nnM, respectivley.

Description of Crizotinib: Crizotinib is an orally bioavailable agent belonging to the class of c-met/hepatocyte growth factor receptor (HGFR) tyrosine kinase inhibitors with potential antineoplastic activity. Crizotinib was approved for treatment of some non-small cell lung carcinoma (NSCLC) in the US, and undergoing clinical trials testing its safety and efficacy in anaplastic large cell lymphoma, neuroblastoma, and other advanced solid tumors in both adults and childre. Crizotinib inhibits the membrane receptor MET and activation of the MET signaling pathway, which may block tumor cell growth, migration and invasion, and tumor angiogenesis in susceptible tumor cell populations. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus) .

For the detailed information about the solubility of Crizotinib (PF-2341066) in water, the solubility of Crizotinib (PF-2341066) in DMSO, the solubility of Crizotinib (PF-2341066) in PBS buffer, the animal experiment of Crizotinib (PF-2341066),the in vivo and in vitro test of Crizotinib (PF-2341066),the cell experiment of Crizotinib (PF-2341066),the IC50 and EC50 of Crizotinib (PF-2341066)please contact DC Chemicals.