Flavopiridol |cas 146426-40-6 |DC Chemicals|Supplier|Price|Buy

DC Chemicals Supply: Flavopiridol ,cas 146426-40-6, Cat No. DC2014, In stock

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Product name: Flavopiridol, Synonym:　HMR-1275, L86-8275, Cat No. DC2014, Cas: 146426-40-6, Chemical Name:2-(2-chlorophenyl)-5,7-dihydroxy-8-((3S,4R)-3-hydroxy-1-methylpiperidin-4-yl)-4H-chromen-4-one hydrochloride, Molecular Formula: C21H20ClNO5.HCl, MW: 438.3

Flavopiridol Cas#146426-40-6.Purity:99%.Best Price and Quality in the Market!Supplied by DC Chemicals! Flavopiridol competes with ATP to inhibit CDKs including CDK1, CDK2, CDK4 and CDK6 with IC50 of ~ 40 nM, and CDK7 with IC50 of 300 nM.

Alvocidib is a synthetic N-methylpiperidinyl chlorophenyl flavone compound. As an inhibitor of cyclin-dependent kinase, alvocidib induces cell cycle arrest by preventing phosphorylation of cyclin-dependent kinases (CDKs) and by down-regulating cyclin D1 and D3 expression, resulting in G1 cell cycle arrest and apoptosis. This agent is also a competitive inhibitor of adenosine triphosphate activity. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)

For the detailed information about the solubility of Flavopiridol in water, the solubility of Flavopiridol in DMSO, the solubility of Flavopiridol in PBS buffer, the animal experiment of Flavopiridol,the in vivo and in vitro test of Flavopiridol,the cell experiment of Flavopiridol,the IC50 and EC50 of Flavopiridolplease contact DC Chemicals.