2017年11月21日星期二

MPI-5a|cas 1259296-46-2

MPI-5a|cas 1259296-46-2

DC Chemicals, Website: www.dcchemicals.com

Product Name: MPI-5a|Cas Number: 1259296-46-2| Catalog Number: DC10063|Other Nmaes: MPI 5a,MPI5a

MPI_5a is a potent selective inhibitor of HDAC6, and poorly blocks other HDAC enzymes.

MPI_5a is a potent selective inhibitor of HDAC6, and poorly blocks other HDAC enzymes. HDAC6 is a predominantly cytoplasmic enzyme that targets α-tubulin, cortactin, and heat shock protein 90, and other substrates. MPI-5a has an IC50 of 36 nM in tumour cell models and inhibits the acetylation of tubulin in cells with an IC50 value of 210 nM.

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