Campesterol |cas 474-62-4

Campesterol |cas 474-62-4

DC Chemicals, Website: www.dcchemicals.com

Product Name: Campesterol|Cas Number: 474-62-4| Catalog Number: DC10377|Other Nmaes: (24R)-5-Ergosten-3β-ol

Campesterol is a plant sterol with cholesterol lowering and anticarcinogenic effects.

Campesterol shows a weak cytotoxicity in non-proliferating human umbilical vein endothelial cells (HUVECs). Within the non-cytotoxic concentration range, campesterol significantly inhibits the bFGF-induced proliferation and tube formation of HUVECs in a concentration-dependent manner, while it does not affect the motility of HUVECs. 50 μg/mL of campesterol decreases the cell viability up to about 56% of control(IC50 of over 50 μg/mL)[1].Campesterol effectively disrupts the bFGF-induced neovascularization in chick chorioallantoic membrane (CAM) in vivo[1].