ML-281|ML281|STK33 inhibitor

ML-281|ML281|STK33 inhibitor

ML281 in stock,price: 550 USD/100mg. ML281 is a potent and selective STK33 inhibitor with IC50 of 14 nM. ML281 showed a 550-fold selectivity over AurB and greater than 700-fold selectivity over PKA.

Product Name: ML281 |cas: 1404437-62-2 |cat number: DC9820 |Molecule Formular: C22H19N3O2S |MW: 389.47 |purity>98%

ML281 is a potent and selective STK33 inhibitor with IC50 of 14 nM. ML281 showed a 550-fold selectivity over AurB and greater than 700-fold selectivity over PKA.ML281 showed low nanomolar inhibition of purified recombinant STK33 and a distinct selectivity profile as compared to other STK33 inhibitors. Even at the highest concentration tested (10 μM), ML281 had no effect on the viability of KRAS-dependent cancer cells.

For research only, not for human use.