GSK6853|GSK-6853|BRPF1 bromodomain inhibitor

GSK6853|GSK-6853|BRPF1 bromodomain inhibitor

GSK6853 is a potent, soluble, cell active, and highly selective inhibitor of the BRPF1 bromodomain

Product Name: GSK6853 |cas: 1910124-24-1 |cat number: DC9831 |Molecule Formular: C22H27N5O3 |MW: 409.21 |purity>98%

GSK6853 is a potent (300 pM), soluble, cell active (20 nM), and highly selective inhibitor of the BRPF1 bromodomain, and demonstrated properties suitable for cellular and in vivo studies.The BRPF (Bromodomain and PHD Finger-containing) protein family are important scaffolding proteins for assembly of MYST histone acetyltransferase complexes. A selective benzimidazolone BRPF1 inhibitor showing micromolar activity in a cellular target engagement assay was recently described.

For research only, not for human use.