Tipifarnib|cas 192185-72-1|DC Chemicals

Tipifarnib|cas 192185-72-1|DC Chemicals

Tipifarnib (IND 58359; R115777) is a potent and specific farnesyltransferase inhibitor with an IC50 of 0.6 nM.

Product name: Tipifarnib|Purity>98%| CAS: 192185-72-1|Molecule Formular: C27H22Cl2N4O|MW: 489.4|Other Namess: Zarnestra; IND 58359; R115777; IND-58359; IND58359; R-115777; R 115777

Tipifarnib (IND 58359; R115777) is a potent and specific farnesyltransferase inhibitor with an IC50 of 0.6 nM.
Tipifarnib is a nonpeptidomimetic quinolinone with potential antineoplastic activity. Tipifarnib (Zarnestra; IND 58359; R115777) binds to and inhibits the enzyme farnesyl protein transferase, an enzyme involved in protein processing (farnesylation) for signal transduction. By inhibiting the farnesylation of proteins, it prevents the activation of Ras oncogenes, inhibits cell growth, induces apoptosis, and inhibits angiogenesis.

For research only, not for human use.