BMS-707035 (CAS 729607-74-3)|HIV-I integrase inhibitor

BMS-707035 (CAS 729607-74-3)|HIV-I integrase inhibitor

BMS-707035 is a potent, specific, and reversible HIV-I integrase (IN) inhibitor that blocks HIV IN strand transfer activity.

Product name: BMS-707035|Purity>98%| CAS: 729607-74-3|Molecule Formular: C17H19FN4O5S|MW: 410.42|Other Namess: BMS 707035，BMS707035

BMS-707035 is a pyrimidine carboxamide similar to Raltegravir. BMS-707035 is a potent, specific, and reversible HIV-I integrase (IN) inhibitor that blocks HIV IN strand transfer activity. BMS-707035 binding and target DNA binding to IN are mutually exclusive events, as elucidated by the fact that increasing the amount of target DNA overcomes the inhibition of strand transfer catalysis by BMS-707035. BMS-707035 binding affinity to IN is also affected by the four terminal bases at the 5’ end of the pre-processed U5 long terminal repeat (LTR).

For research only, not for human use.