2017年11月21日星期二

T-5601640(T56-LIMKi)LIMK2 inhibitor

T-5601640(T56-LIMKi)LIMK2 inhibitor

DC Chemicals, Website: www.dcchemicals.com

Product Name: T-5601640(T56-LIMKi)|Cas Number: 924473-59-6| Catalog Number: DC10067|Other Nmaes: T5601640,T 5601640,T56-LIMKi

T56-LIMKi is a LIMK2 inhibitor that reduces phosphorylated cofilin, and induces disassembly of actin stress fibers in NF1-/- MEFs cells.

Selective LIM kinase 2 (LIMK2) inhibitor; inhibits cofilin phosphorylation in cells that overexpress LIMK2 but not LIMK1. Attenuates the growth of several cancer cell lines. Reduces phospho-cofilin levels and Panc-1 tumor size in a mouse xenograft model.

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