NQ301|NQ-301|CD45 inhibitor

NQ301|NQ-301|CD45 inhibitor

DC Chemicals, Website: www.dcchemicals.com

Product Name: NQ301|Cas Number: 130089-98-4| Catalog Number: DC9999|Other Nmaes: NQ 301, NQ-301

NQ301 is a selective CD45 inhibitor (IC50 = 200 nM). Exhibits >200-fold selectivity for CD45 over six related protein tyrosine phosphatases.

NQ301 is a selective CD45 inhibitor (IC50 = 200 nM). Exhibits >200-fold selectivity for CD45 over six related protein tyrosine phosphatases. NQ301 increases phosphorylation of Lck in Jurkat cells and reduces T cell receptor signaling in acitvated splenocytes in vitro. Blocks inflammation in a delayed-type hypersensitivity model in vivo.