LTURM34 |cas 1879887-96-3
DC Chemicals, Website: www.dcchemicals.com
Product Name: LTURM34|Cas Number: 1879887-96-3| Catalog Number: DC10155|Other Nmaes: LTURM 34; LTURM-34
LTURM34 is a specific DNA-PK inhibitor with an IC50 of 0.034 μM.
LTURM34 shows potent inhibition of DNA-PK with excellent selectivity over the Class I PI3K isoforms. The IC50s are 5.8 and 8.5 μM for PI3K β and δ, respectively. LTURM34 shows potent and broad ranging antiproliferative activity. LTURM34 is more consistently active against the selected cell lines (11 of 16), but at best shows 54% inhibition against the HOP-92 non-small cell lung cancer line[1].
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