DREADD Agonist 21|CAS 56296-18-5

DREADD Agonist 21|CAS 56296-18-5

DC Chemicals, Website: www.dcchemicals.com

Product Name: DREADD Agonist 21|Cas Number: 56296-18-5| Catalog Number: DC10039

DREADD agonist 21 is a potent muscarinic hM3Dq DREADD agonist (EC50 = 1.7 nM). Highly selective for hM3Dq DREADDs over endogenous hM3 receptors.

DREADD agonist 21 activates hM3Dq (EC50 = 1.7 nM), a designer receptor exclusively activated by designer drugs (DREADD) derived from the human muscarinic acetylcholine M3 receptor.It does not agonize the hM3 receptor and displays relatively weaker binding affinities for serotonin 5HT2A, 5HT2C, α1A-adrenergic, and histamine H1 receptors (Kis = 66, 170, 280, and 6 nM, respectively).