AZ9482|cas 1825345-33-2

AZ9482|cas 1825345-33-2

DC Chemicals, Website: www.dcchemicals.com

Product Name: AZ9482|Cas Number: 1825345-33-2| Catalog Number: DC10056|Other Nmaes: AZ 9482,AZ-9482

AZ9482, a potent and selective PARP inhibitor featuring an amide linkage to a 2-piperazinyl-3-cyano-pyridine.

AZ9482, a potent and selective PARP inhibitor featuring an amide linkage to a 2-piperazinyl-3-cyano-pyridine. AZ9482 exhibits very potent centrosome declustering activity in HeLa cells (EC50 < 18 nM).

AZ9482 also showed a 3 nM GI50 in the DLBCL cell line OCI-LY-19 in a 3-day AlamarBlue assay. Consistent with published siRNA knockdown experiments, AZ9482 was a 9 nM enzyme inhibitor of tankyrase 1 (TNKS1).