2017年11月20日星期一

APS-2-79|KSR/RAS signaling modulator

APS-2-79|KSR/RAS signaling modulator

DC Chemicals, Website: www.dcchemicals.com

Product Name: APS-2-79|Cas Number: 2002381-25-9| Catalog Number: DC10048|Other Nmaes: APS 2 79,APS279,APS-279

APS-2-79 is a novel modulator of KSR-dependent MAPK signalling,KSR2,IC50=120 nM

APS-2-79 is a novel modulator of KSR-dependent MAPK signalling, antagonizing RAF heterodimerization as well as the conformational changes required for phosphorylation and activation of KSR-bound MEK (mitogen-activated protein kinase)

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