URB602|URB-602|monoglycerol lipase (MGL) INHIBITOR

URB602|URB-602|monoglycerol lipase (MGL) INHIBITOR

DC Chemicals, Website: www.dcchemicals.com

Product Name: URB602|Cas Number: 565460-15-3| Catalog Number: DC9990|Other Nmaes: URB 602,URB-602

URB602 is a selective inhibitor of monoglycerol lipase (MGL), exhibiting an IC50 of 28 µM for the rat brain enzyme.

Monoacylglycerol Lipase Inhibitor, URB602 is a cell-permeable N-biphenyl carbamate compound that has been found to act as a non-competitive and selective inhibior of Monoglyceride Lipase (monoacylglycerol lipase, MAGL). Monoacylglycerol Lipase Inhibitor, URB602 has not been found to inhibit FAAH, COX-2, or diacylglycerol lipase activity. Monoacylglycerol Lipase Inhibitor, URB602 has been shown to increase antinociception induced by stress, most likely through increasing 2-arachidonylglycerol levels.