Centrinone| Plk4 inhibitor|cas 1798871-30-3
DC Chemicals, Website: www.dcchemicals.com
Product Name: Centrinone|Cas Number: 1798871-30-3| Catalog Number: DC10010
Centrinone is a selective and reversible inhibitor of polo-like kinase 4 (Plk4), a serine-threonine protein kinase that initiates centriole/centrosome assembly.
Centrinone is a selective and reversible inhibitor of polo-like kinase 4 (Plk4), a serine-threonine protein kinase that initiates centriole/centrosome assembly.
Centrinone has been used to reversibly remove centrosomes from human and other vertebrate cells. Treatment with Centrinone at sub-micromolar concentrations allows persistent and reversible depletion of centrioles from cultured human and mouse cells, leading to loss of centrosomes and primary cilia.
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