A-740003|cas 861393-28-4| DC Chem|Supplier|Price|Buy  

A-740003|cas 861393-28-4| DC Chem|Supplier|Price|Buy

DC Chemicals Supply: A-740003, Cas: 861393-28-4 ,Cat No. DC7351, Purity>98%, In stock.

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A-740003|cas 861393-28-4, Synonym name: A 740003; A740003, Chemical name:　N-[1-[(E)-[(cyanoamino)-(quinolin-5-ylamino)methylidene]amino]-2,2-dimethylpropyl]-2-(3,4-dimethoxyphenyl)acetamide, Molecule weight: 474.57, Molecule Formula: C26H30N6O3

A-740003 is potent, selective and competitive P2X7 receptor antagonist (IC50 values are 18 and 40 nM for rat and human receptors respectively).

A-740003 is potent, selective and competitive P2X7 receptor antagonist (IC50 values are 18 and 40 nM for rat and human receptors respectively). A-740003 displays selectivity over a variety of P2X and P2Y receptors up to a concentration of 100 μM. A-740003 reduces nociception in animal models of persistent neuropathic and inflammatory pain.