Delafloxacin|cas 189279-58-1| DC Chem|Supplier|Price|Buy

Delafloxacin|cas 189279-58-1| DC Chem|Supplier|Price|Buy

DC Chemicals Supply: Delafloxacin, Cas: 189279-58-1 ,Cat No. DC7400, Purity>98%, In stock.

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Delafloxacin|cas 189279-58-1, Synonym name: Delafloxacinum; RX-3341; WQ-3034; ABT492; ABT 492; ABT-492, Chemical name:　, Molecule weight: 440.76, Molecule Formula: C18H12ClF3N4O4

Delafloxacin (RX-3341, ABT-492) is a fluoroquinolone antibiotic agent.

IC50 Value: MICs ranging from 0.0078 to 0.125 micro g/ml for levofloxacin-resistant Streptococcus pneumoniae strains [1]

ABT-492 was more potent against quinolone-susceptible and -resistant gram-positive organisms, had activity similar to that of ciprofloxacin against certain members of the family Enterobacteriaceae, and had comparable activity against quinolone-susceptible, nonfermentative, gram-negative organisms.

in vitro: ABT-492 exhibited excellent in vitro activities against all 326 aerobic and anaerobic antral puncture sinus isolates tested with MICs (in micrograms per milliliter) at which 90% of the isolates tested were inhibited as follows: Haemophilus influenzae, 0.001; Moraxella catarrhalis, 0.008; and Streptococcus pneumoniae, 0.015 [2]. ABT-492 was as active as trovafloxacin against Chlamydia trachomatis, indicating good intracellular penetration and antibacterial activity [3].